It’s kind of difficult to do a “running commentary” of Hotel Dusk, as it has so many plot twists that I’d ruin the game for anyone reading who is going to play it for themselves.
I can, however, say a little. Firstly, I’ve noticed that each chapter seems to focus on certain characters more than others. For example, one chapter is mainly about the little girl you meet right near the start of the game (and her parents), one is mostly about Louie/Louis (make your mind up, Cing!), and Chapter 4 was mainly about the author.
I’m now part way through Chapter 5, and I’ve just finished “chatting” with the spooky girl wot can’t speak.